Library

Melanotan 2

Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis to facilitate tanning. It may also increase sexual arousal. Melanotan II was originally developed as a tanning agent based on an earlier drug called afamelanotide, which is now approved by the FDA for the treatment of a particular rare genetic form of sun sensitivity. Melanotan II was later investigated as a potential treatment for sexual dysfunction, but development was abandoned in 2000 in order to pursue development of bremelanotide, a chemically similar drug later approved by the FDA for treatment of sexual dysfunction in women. Unlicensed melanotan II is found on the internet, although health agencies advise against its use due to legality, case reports suggesting significant safety risks, and potential impurities.