Methylone is a synthetic stimulant and entactogen of the cathinone class. First synthesized by Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant, it later gained popularity as a recreational substance. Methylone is frequently used as a substitute for MDMA due to overlapping effects, though Shulgin himself described it as lacking MDMA's "unique magic," noting it is more stimulating and less empathogenic. It has been commonly mis-sold as MDMA.
Metylón molecular structure diagram from the DrugsPRO substance library.
Also known as: M1, Mdmc, Ease, Bk-mdma, Explosion, Beta-keto-MDMA, MDMCAT, Molly
Classification
Chemical: Cathinone
Chemical: Phenethylamine
Psychoactive: Entactogen
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Common
Tag: Empathogen
Tag: Habit-Forming
Tag: Research-Chemical
Effects
Spontaneous Tactile Sensations
Stimulation
Temperature Regulation Suppression
Difficulty Urinating
Increased Blood Pressure
Increased Heart Rate
Euphoria
Empathy Love And Sociability Enhancement
Time Distortion
Unity And Interconnectedness
Thought Acceleration
Mindfulness
Tactile Enhancement
Vibrating Vision
Dehydration
Increased Libido
Increased Music Appreciation
Open Eye Visuals
Routes of Administration
Oral
Dosage
Heavy: 270+ mg
Light: 60 – 150 mg
Common: 150 – 225 mg
Strong: 225 – 270 mg
Threshold: 60–120 mg
Duration
Onset: 0.25-0.75 h
Comeup: 0.25-0.75 h
Peak: 1-1.5 h
Offset: 1-1.5 h
After Effects: 6-24 h
Total Duration: 2-5 h
Insufflated
Dosage
Heavy: 220+ mg
Light: 40–80 mg
Common: 80–150 mg
Strong: 150–220 mg
Threshold: 20–40 mg
Duration
Onset: 0.08-0.33 h
Peak: 0.5-1.5 h
Offset: 1.5-3.5 h
After Effects: 2.5-18 h
Total Duration: 1.5-3.5 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Methylone - DrugsPRO sprievodca látky
Methylone: Methylone is a synthetic stimulant and entactogen of the cathinone class. First synthesized by Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant, it later gained popularity as a recreational substance. Methylone is frequently used as a substitute for MDMA due to
