Eszopiklon

Eszopiclone is a nonbenzodiazepine hypnotic of the cyclopyrrolone class and the active S-stereoisomer of zopiclone. It belongs to the family of drugs colloquially known as "Z-drugs." First approved by the FDA in 2004 for the treatment of insomnia, it is notable for being one of few hypnotic sedatives approved for long-term use. Eszopiclone enhances GABAergic neurotransmission in a manner similar to yet distinct from benzodiazepines and is considered habit-forming.

Also known as: Eszop, Lunesta

Classification

Chemical: Medicine
Chemical: Z-drug
Psychoactive: Depressant
Psychoactive: Psychedelic
Tag: Cyclopyrrolone
Tag: Habit-Forming
Tag: Hallucinogen
Tag: Hypnotic

Effects

Sedation
Muscle Relaxation
Headache
Nausea
Dry Mouth
Anxiolytic
Cognitive Fatigue
Amnesia
Anxiety Suppression
Emotion Suppression
Motor Control Loss
Dizziness
Disinhibition
Internal Hallucination
External Hallucination
Dulled Perception
Taste Distortion
Color Enhancement

Routes of Administration

Oral

Dosage

Heavy: 6 mg
Light: 0.5 – 2 mg
Common: 2 – 3 mg
Strong: 3 – 6 mg
Threshold: 0.5 mg

Duration

Onset: 0.17-0.33 h
Peak: 0.5-1.5 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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