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Meflokin

Mefloquine is an antimalarial medication with significant CNS effects. It can cause serious and potentially permanent neuropsychiatric side effects including anxiety, depression, hallucinations, psychosis, and suicidal ideation, occurring in approximately 1 in 10,000 users for prophylaxis. These effects may persist for months to years after discontinuation or be permanent. It is contraindicated in individuals with a history of psychiatric disorders, depression, anxiety disorders, psychosis, schizophrenia, or seizures. Not recommended for severe malaria.

Meflokin molecular structure
Meflokin molecular structure diagram from the DrugsPRO substance library.

Also known as: Lariam, Wr142490, Mephaquin, Wr-177602, RO 21-5998, Mefloquinum, Mefloquina

Classification

  • Chemical: Medicine
  • Tag: Antimalarial
  • Tag: Prescription-medication
  • Tag: Quinoline methanol derivative

Effects

  • Vertigo
  • Headache
  • Sleep Disturbances
  • Balance Problems
  • Nausea
  • Vomiting
  • Dizziness
  • Vivid Dreams
  • Nightmares
  • Anxiety
  • Depression
  • Paranoia
  • Visual Hallucinations
  • Auditory Hallucination
  • Tinnitus
  • Ringing
  • Open Eye Visuals

Routes of Administration

Oral

Dosage

  • Common: 250 mg weekly (prophylaxis); 1250 mg single dose (treatment)

Duration

  • Peak: 168-240 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Mefloquine - DrugsPRO vodič po substancah

Mefloquine: Mefloquine is an antimalarial medication with significant CNS effects. It can cause serious and potentially permanent neuropsychiatric side effects including anxiety, depression, hallucinations, psychosis, and suicidal ideation, occurring in approximately 1 in 10,000 users for prophylaxi

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