Desoxyn is pharmaceutical dextromethamphetamine prescribed for ADHD and rarely for severe obesity. It is significantly more potent and longer-lasting than amphetamine, with greater abuse and addiction potential. Methamphetamine is directly neurotoxic to dopamine and serotonin neurons, particularly at recreational doses. The dextro enantiomer is a stronger CNS stimulant than the levo form. Use carries extreme risks including addiction, cardiovascular complications, psychosis, and severe neurotoxicity with chronic use.
Metamfetamin molecular structure diagram from the DrugsPRO substance library.
Also known as: Desoxyn, T, Tik, Ice, Meth, Sisa, Crystal, Glass, Shards, Tina, Tweak, Crank, Shabu, Metamfetamine
Classification
Chemical: Amphetamine
Psychoactive: Stimulant
Tag: Common
Tag: Habit-Forming
Effects
Stimulation
Physical Euphoria
Stamina Enhancement
Increased Energy
Teeth Grinding
Increased Bodily Temperature
Euphoria
Cognitive Euphoria
Motivation Enhancement
Focus Enhancement
Increased Sociability
Empathy Enhancement
Appetite Suppression
Increased Libido
Increased Music Appreciation
Dehydration
Tactile Hallucination
Visual Drifting
Routes of Administration
Oral
Dosage
Threshold: 2.5 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 60 mg
Heavy: 40-100 mg
Bioavailability: 100 mg
Duration
Onset: 0.33-0.75 h
Comeup: 0.5-1 h
Peak: 3-5 h
Offset: 6-12 h
After Effects: 12-36 h
Total Duration: 8-12 h
Insufflated
Dosage
Threshold: 2.5 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 60 mg
Heavy: 60+ mg
Bioavailability: >90%
Duration
Onset: 0.05-0.08 h
Comeup: 0.25-0.5 h
Peak: 1.5-3 h
Offset: 2-4 h
After Effects: 6-24 h
Total Duration: 2-6 h
Smoked
Dosage
Threshold: 2.5 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 60 mg
Heavy: 60+ mg
Bioavailability: >90%
Duration
Onset: 0-0.03 h
Comeup: 0-0 h
Peak: 0.33-2 h
Offset: 1-3 h
After Effects: 2-24 h
Total Duration: 1-4 h
Rectal
Dosage
Heavy: 50 mg
Light: 5 – 15 mg
Common: 15 – 30 mg
Strong: 30 – 50 mg
Threshold: < 5 mg
Bioavailability: ~99% [2]
Duration
Onset: 0.08-0.25 h
Comeup: 0.05-0.08 h
Peak: 2-4 h
Offset: 3-5 h
After Effects: 6-24 h
Intravenous
Dosage
Heavy: 60+ mg
Light: 5 – 10 mg
Common: 10 – 30 mg
Strong: 30 – 60 mg
Threshold: 5 mg
Bioavailability: ~100% [1]
Duration
Onset: 0-0.01 h
Comeup: 0.02-0.03 h
Peak: 0.1-2 h
Offset: 2-4 h
After Effects: 6-24 h
Total Duration: 4-8 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Methamphetamine - DrugsPRO vodič po substancah
Methamphetamine: Desoxyn is pharmaceutical dextromethamphetamine prescribed for ADHD and rarely for severe obesity. It is significantly more potent and longer-lasting than amphetamine, with greater abuse and addiction potential. Methamphetamine is directly neurotoxic to dopamine and serotonin neuron
