Muscimol, also known as agarin, pantherine, or pyroibotenic acid, is a GABAA receptor agonist with sedative and hallucinogenic effects and the principal psychoactive constituent of Amanita mushrooms such as Amanita muscaria and Amanita pantherina. It is a 3-hydroxyisoxazole alkaloid and is closely related structurally to the neurotransmitter γ-aminobutyric acid (GABA). The compound is widely used as a ligand and agonist of the GABAA receptor in scientific research. Muscimol is typically taken orally, but may also be smoked. Peak effects occur after 1 to 3 hours orally and its duration is 4 to 10 hours but up to 24 hours.
Muscimol molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Tryptamine
Psychoactive: Psychedelic
Tag: Plant-based
Effects
Dilated Pupils
Sedation
Nausea
Physical Euphoria
Pupil Dilation
Stimulation
Introspection
Confusion
Time Distortion
Euphoria
Anxiety
Visual Distortion
Color Enhancement
Drifting
Auditory Distortion
Color Shifting
Routes of Administration
No route information available yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Muscimol - DrugsPRO vodič po substancah
Muscimol: Muscimol, also known as agarin, pantherine, or pyroibotenic acid, is a GABAA receptor agonist with sedative and hallucinogenic effects and the principal psychoactive constituent of Amanita mushrooms such as Amanita muscaria and Amanita pantherina. It is a 3-hydroxyisoxazole alkaloid and is
