Ondansetron

Ondansetron is classified as Antiemetic (not psychoactive in the traditional sense; centrally and peripherally acts on emesis pathways). It belongs to the Carbazole derivative (selective serotonin 5-HT3 receptor antagonist) chemical class.

Also known as: Zofran, Zuplenz

Classification

Chemical: Medicine
Tag: Pharmaceutical

Effects

Nausea
Vomiting
Dizziness

Routes of Administration

Oral

Dosage

Heavy: 24 mg (oncology context only)
Light: 4 mg
Common: 4–8 mg
Strong: 8–16 mg
Threshold: 2 mg

Duration

Onset: 0.5-1 h
Peak: 1-2 h
Offset: 4-12 h
After Effects: 0-6 h
Total Duration: 4-12 h

Intravenous

Dosage

Heavy: >16 mg (not recommended due to QT risk)
Light: 4 mg
Common: 4–8 mg
Strong: 8–12 mg
Threshold: 2 mg

Duration

Onset: 0-0.25 h
Peak: 0.25-1 h
Offset: 4-8 h
After Effects: 0-4 h
Total Duration: 4-8 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

openFDA.gov

Links

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