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4F-4-MAR

4F-4-MAR first appeared in Slovenia (2018) and was forensically confirmed via HR-MS and NMR. The para-fluoro substitution raises lipophilicity and slows oxidative metabolism, explaining >16 hour subjective duration. User reports highlight pronounced anorexia, clean but long-lasting stimulation and muted euphoria compared to classic 4-MAR. Oral dosing is markedly more effective than nasal; vaporization yields harsh pyrolysis products and is strongly discouraged. As with all aminorex derivatives, pulmonary arterial hypertension remains a serious long-term risk—regular echocardiograms are advised for frequent users.

Also known as: 4-fpo, 4f-mar, Pf-4-mar, Para-fluoro-4-methylaminorex, 4F-4-MAR

Classification

  • Chemical: Aminorex
  • Psychoactive: Stimulant
  • Tag: Research-Chemical

Effects

  • Stimulation
  • Increased Heart Rate
  • Vasoconstriction
  • Bruxism
  • Insomnia
  • Loss Of Appetite
  • Focus Enhancement
  • Motivation Enhancement
  • Euphoria
  • Anxiety
  • Increased Focus
  • Panic
  • Appetite Suppression
  • Light Sensitivity
  • Increased Libido
  • Dehydration
  • Bodily Control Enhancement
  • Increased Music Appreciation

Routes of Administration

Oral

Dosage

  • Threshold: 5 mg
  • Light: 10-20 mg
  • Common: 20-35 mg
  • Strong: 35-50 mg
  • Heavy: 50+ mg

Duration

  • Onset: 0.25-0.75 h
  • Comeup: 0.5-1.5 h
  • Peak: 2-6 h
  • Offset: 6-10 h
  • After Effects: 18-36 h
  • Total Duration: 12-24 h

Insufflated

Dosage

  • Threshold: 10-20 mg
  • Light: 15-40 mg
  • Common: 40-80 mg
  • Strong: 80-120 mg
  • Heavy: 120+ mg

Duration

  • Onset: 0.08-0.25 h
  • Comeup: 0.25-0.75 h
  • Peak: 1.5-4 h
  • Offset: 6-10 h
  • After Effects: 12-30 h
  • Total Duration: 10-20 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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4F-4-MAR - DrugsPRO vodič o supstancama

4F-4-MAR: 4F-4-MAR first appeared in Slovenia (2018) and was forensically confirmed via HR-MS and NMR. The para-fluoro substitution raises lipophilicity and slows oxidative metabolism, explaining >16 hour subjective duration. User reports highlight pronounced anorexia, clean but long-lasting stimula

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