4-МПП

para-Methylphenylpiperazine (pMPP; code name PAL-233), or 4-methylphenylpiperazine (4-MPP or 4-Me-PP), is a designer drug and monoamine releasing agent of the phenylpiperazine family. It is a serotonin releasing agent, with an EC50Tooltip half-maximal effective concentration of 220 nM in rat brain synaptosomes, and was inactive in the case of norepinephrine and dopamine (EC50 = >10,000 nM and >20,000 nM, respectively). It shows very low potency as a dopamine reuptake inhibitor, with an IC50Tooltip half-maximal inhibitory concentration of 9,523 nM, whereas serotonin and norepinephrine were not reported. Possible activities at serotonin receptors have not been reported.

Classification

Psychoactive: Stimulant

Effects

Increased Heart Rate
Stimulation
Talkativeness
Alertness Enhancement
Light Sensitivity

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

wikipedia.org

Links

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