Lean, also called purple drank or sizzurp, is a non-standard mixture usually made from codeine and promethazine cough syrup. Codeine is an opioid that is partly converted to morphine, while promethazine adds sedative and anticholinergic effects; product strength and individual codeine metabolism can therefore make effects unusually unpredictable. The combination can cause profound drowsiness and respiratory depression, and mixing it with alcohol, benzodiazepines, other opioids, gabapentinoids, GHB/GBL, barbiturates, or other sedatives greatly increases overdose risk.
Also known as: Purple drank, Syrup, Sizzurp, Drank, Barre, Texas tea, Wock
Classification
Chemical: Opioid
Psychoactive: Depressant
Tag: Antihistamine
Tag: Habit-Forming
Tag: Mixture
Effects
Muscle Relaxation
Sedation
Itching
Dry Mouth
Incoordination
Nausea
Euphoria
Drowsiness
Thought Slowing
Reduced Anxiety
Anxiety Suppression
Confusion
Dulled Perception
Blurred Vision
Auditory Hallucination
Cognitive Dysphoria
Perception Of Bodily Heaviness
Auditory Distortion
Routes of Administration
Oral
Dosage
Heavy: 90 mL+ (≥3 oz; strongly discouraged)
Light: 10–20 mL
Common: 20–60 mL (≈1–2 oz)
Strong: 60–90 mL (≈2–3 oz)
Threshold: 5–10 mL (½–1 teaspoon)
Duration
Onset: 0.25-1 h
Peak: 1-2 h
Offset: 2-4 h
After Effects: 4-12 h
Total Duration: 3-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
No external data sources listed for this substance yet.
Links
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Lean - DrugsPRO vodič o supstancama
Lean: Lean, also called purple drank or sizzurp, is a non-standard mixture usually made from codeine and promethazine cough syrup. Codeine is an opioid that is partly converted to morphine, while promethazine adds sedative and anticholinergic effects; product strength and individual codeine metaboli