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2-TFMXP

2-TFMXP is the 2-trifluoromethyl analogue of methoxphenidine (MXP). Very little formal pharmacology is published; all dosing is extrapolated from user reports and structural activity relationships. Compared with MXP it appears 1.5-2× more potent and noticeably more stimulating with increased mania potential. Marked inter-individual variability exists; some users report minimal effects below 30 mg while others reach full dissociation at 25 mg. Start low and titrate carefully.

Also known as: 2-tfm-mxp, TFMXP, 2‑trifluoromethyl‑MXP, 2‑TFM‑diphenidine

Classification

  • Chemical: Diarylethylamine
  • Psychoactive: Dissociative
  • Tag: Research-Chemical

Effects

  • Stimulation
  • Somatic Lightness
  • Pain Relief
  • Incoordination
  • Impaired Balance
  • Numbness
  • Depersonalization
  • Derealization
  • Motor Control Loss
  • Euphoria
  • Time Distortion
  • Conceptual Thinking
  • Perception Of Bodily Lightness
  • Tactile Suppression
  • Spatial Disorientation
  • Visual Disconnection
  • Increased Music Appreciation
  • Internal Hallucination

Routes of Administration

Oral

Dosage

  • Threshold: 5-10 mg
  • Light: 10-25 mg
  • Common: 25-45 mg
  • Strong: 45-70 mg
  • Heavy: 70 mg+ (NOT RECOMMENDED)

Duration

  • Onset: 0.33-1 h
  • Comeup: 0.5-1 h
  • Peak: 1.5-4 h
  • Offset: 2-4 h
  • After Effects: 8-24 h
  • Total Duration: 6-10 h

Sublingual

Dosage

  • Threshold: 4-8 mg
  • Light: 8-20 mg
  • Common: 20-40 mg
  • Strong: 40-60 mg
  • Heavy: 60 mg+ (NOT RECOMMENDED)

Duration

  • Onset: 0.17-0.67 h
  • Comeup: 0.33-0.75 h
  • Peak: 1.25-3.5 h
  • Offset: 3.5-8 h
  • After Effects: 8-24 h
  • Total Duration: 6-10 h

Insufflated

Dosage

  • Threshold: 3-5 mg
  • Light: 5-15 mg
  • Common: 15-30 mg
  • Strong: 30-45 mg
  • Heavy: 45 mg+ (NOT RECOMMENDED)

Duration

  • Onset: 0.08-0.25 h
  • Comeup: 0.25-0.5 h
  • Peak: 1.5-4 h
  • Offset: 3-6.5 h
  • After Effects: 6.5-24 h
  • Total Duration: 5-9 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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2-TFMXP - DrugsPRO substansguide

2-TFMXP: 2-TFMXP is the 2-trifluoromethyl analogue of methoxphenidine (MXP). Very little formal pharmacology is published; all dosing is extrapolated from user reports and structural activity relationships. Compared with MXP it appears 1.5-2× more potent and noticeably more stimulating with increase

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