Library
AM-2233
AM-2233 is a full CB1/CB2 agonist with sub-nanomolar affinity; overdose margins are extremely narrow. Weigh doses with a 0.1 mg-resolution scale or use volumetric dosing. CRITICAL WARNING: AM-2233 is notably associated with severe and persistent tinnitus (ringing in the ears), even at moderate doses, which may last for hours to days. Acute adverse events include severe anxiety, panic, auditory hallucinations, visual distortions, tachycardia, hypertension, seizures, acute kidney injury, and rhabdomyolysis. Very limited human data exist; long-term neurotoxicity is unknown.
Also known as: Cs-325
Classification
- Chemical: Cannabinoid
- Chemical: Synthetic cannabinoid
- Tag: Benzoylindole
- Tag: Habit-Forming
- Tag: Hallucinogen
- Tag: Research-Chemical
- Tag: Sedative
Effects
- Body Lightness Or Heaviness
- Sedation
- Analgesia
- Tachycardia
- Dry Mouth
- Nausea
- Rapid Intoxication
- Euphoria
- Time Distortion
- Anxiety
- Paranoia
- Memory Suppression
- Visual Distortion
- Closedeye Imagery
- Tinnitus
- Auditory Suppression
- Closed Eye Visuals
- Open Eye Visuals
Routes of Administration
Smoked
Dosage
- Threshold: 0.25 mg
- Light: 0.5 – 1 mg
- Common: 1 – 2 mg
- Strong: 2 – 4 mg
- Heavy: 4 mg +.
Duration
- Onset: 0.01-0.03 h
- Peak: 0.08-0.33 h
- Offset: 0.5-1.5 h
- After Effects: 2-6 h
- Total Duration: 1-3 h
Oral
Dosage
- Threshold: 1 mg
- Light: 2 – 3 mg
- Common: 3 – 5 mg
- Strong: 5 – 8 mg
- Heavy: 8 mg +.
Duration
- Onset: 0.25-0.75 h
- Peak: 0.75-2 h
- Offset: 0.5-1.5 h
- After Effects: 2-6 h
- Total Duration: 3-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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