Bezitramid

Withdrawn from Dutch market in 2004 following pediatric fatality. Extremely delayed onset encourages dangerous redosing before peak effects manifest. Historical 5 mg tablets represented supratherapeutic doses for opioid-naive users. Prodrug rapidly hydrolyzed to active metabolite despropionyl-bezitramide (R-4618) in gastrointestinal tract.

Also known as: R-4845, Burgodin, Bezitramidum, Bezitramida

Classification

Chemical: Medicine
Chemical: Opioid
Psychoactive: Depressant
Tag: Benzimidazole
Tag: Habit-Forming
Tag: Withdrawn

Effects

Pain Relief
Physical Euphoria
Sedation
Respiratory Depression
Itchiness
Nausea
Cognitive Euphoria
Anxiety Suppression
Euphoria
Sadness
Wakefulness
Motivation Enhancement
Dulled Perception
Appetite Suppression
Light Sensitivity
Internal Hallucination
Size Distortion
Warmth

Routes of Administration

Oral

Dosage

Threshold: 0.25-0.5 mg
Light: 0.5-1 mg
Common: 1-2.5 mg
Strong: 2.5-5 mg
Heavy: 5 mg+

Duration

Onset: 0.5-3.5 h
Peak: 2.5-3.5 h
Offset: 8-12 h
After Effects: 6-12 h
Total Duration: 12-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

dose.wiki

Links

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