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Fenibut

Phenibut is a depressant and anxiolytic of the gabapentinoid class, structurally derived from the neurotransmitter GABA. Developed in the Soviet Union during the 1960s under Professor V. V. Perekalin, it remains a prescribed pharmaceutical in Russia for conditions including anxiety, insomnia, depression, and PTSD. Outside Russia, it is unapproved for clinical use and typically sold as a nutritional supplement. At common doses, it is noted for producing less drowsiness than other GABAergic substances such as benzodiazepines.

Fenibut molecular structure
Fenibut molecular structure diagram from the DrugsPRO substance library.

Also known as: Phgaba, Noofen, Bifren, Fenibut, Anvifen

Classification

  • Chemical: Gabapentinoid
  • Psychoactive: Depressant
  • Psychoactive: Nootropic
  • Tag: Anxiolytic
  • Tag: GABA analogue
  • Tag: GABAergic
  • Tag: Habit-Forming
  • Tag: Research-Chemical

Effects

  • Stimulation And Sedation
  • Respiratory Depression
  • Nausea
  • Increased Perspiration
  • Stomach Cramps
  • Headache
  • Empathy Love And Sociability Enhancement
  • Information Processing Suppression
  • Thought Deceleration
  • Cognitive Euphoria
  • Motivation Enhancement
  • Anxiety Suppression
  • Disinhibition
  • Dehydration
  • Appetite Enhancement
  • Dulled Perception
  • Open Eye Visuals
  • Blurred Vision

Routes of Administration

Oral

Dosage

  • Heavy: 3.5 g
  • Light: 0.5-1 g
  • Common: 1-2 g
  • Strong: 2-3.5 g
  • Threshold: 0.25 g

Duration

  • Onset: 1.5-3 h
  • Comeup: 1.5-3 h
  • Peak: 3-4 h
  • Offset: 4-6 h
  • After Effects: 6-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Phenibut - DrugsPRO substansguide

Phenibut: Phenibut is a depressant and anxiolytic of the gabapentinoid class, structurally derived from the neurotransmitter GABA. Developed in the Soviet Union during the 1960s under Professor V. V. Perekalin, it remains a prescribed pharmaceutical in Russia for conditions including anxiety, insomn

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