1P-LSD

1P-LSD is a semisynthetic lysergamide psychedelic and LSD prodrug, distinguished by a propionyl group on the nitrogen of LSD's indole ring. The compound reached online research-chemical vendors in 2015 after being synthesized as a lawful substitute for LSD. Its subjective effects are widely regarded as nearly identical to those of LSD itself. It is a structural homologue of ALD-52.

Also known as: 1p, 1-propionyl-LSD, 1-propionyl-lysergic acid diethylamide

Classification

Chemical: Lysergamide
Psychoactive: Psychedelic
Tag: Research-Chemical

Effects

Spontaneous Tactile Sensations
Stimulation
Nausea
Increased Salivation
Increased Heart Rate
Pupil Dilation
Thought Acceleration
Novelty Enhancement
Time Distortion
Analysis Enhancement
Personal Bias Suppression
Conceptual Thinking
Tactile Enhancement
Bodily Control Enhancement
Hallucinations
Visual Drifting
Tracers
Symmetrical Texture Repetition

Routes of Administration

Oral

Dosage

Heavy: ≥250 µg (not recommended without significant experience)
Light: 15 – 50 µg
Common: 50 – 125 µg
Strong: 125 – 200 µg
Threshold: 15–25 µg

Duration

Onset: 0.33-1 h
Comeup: 0.75-2 h
Peak: 3-5 h
Offset: 3-5 h
After Effects: 6-24 h
Total Duration: 8-12 h

Sublingual

Dosage

Heavy: ≥250 µg (not recommended without significant experience)
Light: 25–75 µg
Common: 75–150 µg
Strong: 150–225 µg
Threshold: 15–25 µg

Duration

Onset: 0.5-2 h
Peak: 2-6 h
Offset: 2-4 h
After Effects: 8-24 h
Total Duration: 8-12 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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