Flexeril

Cyclobenzaprine is primarily prescribed as a short-term adjunct (2-3 weeks maximum) to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions. It is not effective for muscle spasm due to central nervous system disease. Overdose can cause anticholinergic toxicity including delirium, tachycardia, dry mouth, and urinary retention. There is risk of serotonin syndrome when combined with serotonergic drugs. Use with caution in elderly patients due to increased risk of confusion, cognitive impairment, and cardiac events.

Also known as: Amrix, Fexmid, Mk-130, Cycoflex, Novo-cycloprine, Cyclobenzaprinum, TNX-102

Classification

Psychoactive: Depressant
Tag: Common
Tag: Dibenzocycloheptene
Tag: Habit-Forming
Tag: Muscle Relaxant
Tag: Sedative
Tag: Tricyclic compound

Effects

Sedation
Muscle Relaxation
Physical Euphoria
Dry Mouth
Incoordination
Fatigue
Drowsiness
Cognitive Euphoria
Motor Control Loss
Dizziness
Confusion
Time Distortion
Blurred Vision
Visual Snow
Internal Hallucination
Dulled Perception
Disinhibition

Routes of Administration

Oral

Dosage

Threshold: 2.5 mg
Light: 2.5-5 mg
Common: 5-10 mg
Strong: 10-20 mg
Heavy: 20+ mg

Duration

Onset: 0.5-1 h
Comeup: 0.75-1.5 h
Peak: 2-4 h
Offset: 6-12 h
After Effects: 12-24 h
Total Duration: 8-24 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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