3-HO-PCE is a synthetic dissociative of the arylcyclohexylamine class that emerged on the research chemical market in the 2010s. Unlike its close structural analog 3-HO-PCP, it has no prior precedent in the scientific literature. The compound is noted for producing potent, dose-sensitive dissociative, hallucinogenic, and euphoric effects. It is considered habit-forming, and very limited research exists regarding its pharmacological profile and safety.
Also known as: 3-oh-pce, 3-hydroxy pce, Hydroxyeticyclidine, 3‑hydroxyeticyclidine, 3‑HO‑Eticyclidine, HO‑PCE
Classification
Chemical: Arylcyclohexylamine
Psychoactive: Dissociative
Tag: Habit-Forming
Tag: Hallucinogen
Tag: Research-Chemical
Tag: Tentative
Effects
Physical Disconnection
Sedation
Physical Euphoria
Pain Relief
Difficulty Urinating
Stimulation
Cognitive Disconnection
Euphoria
Anxiety Suppression
Motor Control Loss
Perspective Distortion
Dizziness
Tactile Suppression
Internal Hallucination
Auditory Hallucination
Auditory Distortion
Pattern Recognition Suppression
Scenery Slicing
Routes of Administration
Oral
Dosage
Heavy: 70 mg+
Light: 10 mg
Common: 5 – 10 mg
Strong: 10 – 15 mg
Threshold: 5–10 mg
Duration
Onset: 0.33-0.67 h
After Effects: 5-11 h
Peak: 1-3 h
Offset: 3-6 h
Total Duration: 4-7 h
Insufflated
Dosage
Heavy: 50 mg+
Light: 10–15 mg
Common: 15–30 mg
Strong: 30–50 mg
Threshold: 5 mg
Duration
Onset: 0.17-0.5 h
Peak: 1.3-3 h
Offset: 3.5-4.5 h
After Effects: 4.5-8 h
Total Duration: 4-7 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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3-HO-PCE - довідник з речовин DrugsPRO
3-HO-PCE: 3-HO-PCE is a synthetic dissociative of the arylcyclohexylamine class that emerged on the research chemical market in the 2010s. Unlike its close structural analog 3-HO-PCP, it has no prior precedent in the scientific literature. The compound is noted for producing potent, dose-sensitive d
