Library
DMNPC
DMNPC is a piperidine-based stimulant with binding affinities of approximately 7.6 nM at SERT, 21 nM at DAT, and 34 nM at NET, making it roughly 2.5 times more potent than cocaine at DAT while retaining SSRI-level SERT affinity. The compound blocks voltage-gated sodium channels similar to cocaine, producing local anesthesia and potential cardiac conduction effects. Users report severe mucosal irritation with intranasal use and caustic effects when administered intravenously. Oral administration provides cleaner effects with less vascular strain. Due to its recent emergence in late 2024, pharmacokinetic data is limited and reagent testing plus fentanyl screening is essential.
Classification
- Psychoactive: Stimulant
- Tag: Piperidine
- Tag: Research-Chemical
Effects
- Stimulation
- Physical Euphoria
- Pupil Dilation
- Vasoconstriction
- Increased Heart Rate
- Teeth Grinding
- Cognitive Euphoria
- Focus Enhancement
- Sociability Enhancement
- Motivation Enhancement
- Compulsive Redosing
- Anxiety
- Tactile Enhancement
- Appetite Suppression
- Light Sensitivity
- Increased Sexuality
- Visual And Auditory Hallucinations
- Increased Libido
Routes of Administration
Oral
Dosage
- Threshold: 5 mg
- Light: 5-15 mg
- Common: 15-40 mg
- Strong: 40-60 mg
- Heavy: 60 mg
Duration
- Onset: 0.25-0.5 h
- Comeup: 0.25-0.5 h
- Peak: 0.5-1.5 h
- Offset: 1-2 h
- After Effects: 1-6 h
Insufflated
Dosage
- Threshold: 5 mg
- Light: 5-15 mg
- Common: 15-30 mg
- Strong: 30-50 mg
- Heavy: 50 mg
Duration
- Onset: 0.08-0.17 h
- Comeup: 0.17-0.33 h
- Peak: 0.5-1.5 h
- Offset: 1-2 h
- After Effects: 1-6 h
Intravenous
Dosage
- Threshold: 2 mg
- Light: 2-10 mg
- Common: 10-25 mg
- Strong: 25-40 mg
- Heavy: 40 mg
Duration
- Onset: 0.02-0.08 h
- Comeup: 0.08-0.17 h
- Peak: 0.17-0.75 h
- Offset: 1-2 h
- After Effects: 1-6 h
Vaporized / Smoked
Dosage
- Threshold: 5 mg
- Light: 5-15 mg
- Common: 15-35 mg
- Strong: 35-60 mg
- Heavy: 60 mg
Duration
- Onset: 0.02-0.08 h
- Comeup: 0.08-0.17 h
- Peak: 0.17-0.75 h
- Offset: 1-2 h
- After Effects: 1-6 h
Rectal
Dosage
- Threshold: 5 mg
- Light: 5-15 mg
- Common: 15-30 mg
- Strong: 30-50 mg
- Heavy: 50 mg
Duration
- Onset: 0.17-0.33 h
- Comeup: 0.25-0.5 h
- Peak: 0.5-1.5 h
- Offset: 1-2 h
- After Effects: 1-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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