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Пронітазен

Active in double-digit microgram doses; steep dose-response curve. Volumetric dosing essential due to extreme potency. Multiple naloxone doses may be required for reversal. Powder has appeared mis-sold as ketamine and heroin; lab confirmation strongly advised. Approximately 3 times more potent than fentanyl and 200 times more potent than morphine.

Пронітазен molecular structure
Пронітазен molecular structure diagram from the DrugsPRO substance library.

Also known as: Protonitazene, Propoxynitazene

Classification

  • Chemical: 2-Benzylbenzimidazole opioid
  • Chemical: Opioid
  • Psychoactive: Depressant
  • Tag: Benzimidazole
  • Tag: Habit-Forming
  • Tag: Nitazene
  • Tag: Research-Chemical
  • Tag: Sedative

Effects

  • Physical Euphoria
  • Pain Relief
  • Sedation
  • Itching
  • Nodding
  • Respiratory Depression
  • Cognitive Euphoria
  • Anxiety Suppression
  • Motivation Suppression
  • Euphoria
  • Sadness
  • Compulsive Redosing
  • Warm Flush
  • Dulled Perception
  • Appetite Suppression
  • Light Sensitivity
  • Internal Hallucination
  • Size Distortion

Routes of Administration

Oral

Dosage

  • Threshold: 50 ug
  • Light: 50-100 ug
  • Common: 100-250 ug
  • Strong: 250-500 ug
  • Heavy: 500 µg+

Duration

  • Onset: 0.17-0.33 h
  • Comeup: 0.33-0.67 h
  • Peak: 0.33-1 h
  • Offset: 2-4 h
  • After Effects: 1-2 h
  • Total Duration: 4-6 h

Insufflated

Dosage

  • Threshold: 10 ug
  • Light: 10-50 ug
  • Common: 50-150 ug
  • Strong: 150-300 ug
  • Heavy: 300 µg+

Duration

  • Onset: 0.02-0.08 h
  • Comeup: 0.08-0.25 h
  • Peak: 0.33-1 h
  • Offset: 2-4 h
  • After Effects: 1-2 h
  • Total Duration: 3-5 h

Vaporized

Dosage

  • Threshold: 5 ug
  • Light: 5-25 ug
  • Common: 25-100 ug
  • Strong: 100-200 ug
  • Heavy: 200 µg+

Duration

  • Onset: 0.02-0.08 h
  • Comeup: 0.08-0.17 h
  • Peak: 0.17-0.67 h
  • Offset: 1.5-3 h
  • After Effects: 1-2 h
  • Total Duration: 2-4 h

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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Pronitazene - довідник з речовин DrugsPRO

Pronitazene: Active in double-digit microgram doses; steep dose-response curve. Volumetric dosing essential due to extreme potency. Multiple naloxone doses may be required for reversal. Powder has appeared mis-sold as ketamine and heroin; lab confirmation strongly advised. Approximately 3 times more

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