Normorphine is an opiate analogue, the N-demethylated derivative of morphine, that was first described in the 1950s when a large group of N-substituted morphine analogues were characterized for activity. The compound has relatively little opioid activity in its own right, but is a useful intermediate which can be used to produce both opioid antagonists such as nalorphine, and also potent opioid agonists such as N-phenethylnormorphine. with its formation from morphine catalyzed by the liver enzymes CYP3A4 and CYP2C8.
Нормарфін molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Medicine
Chemical: Opioid
Psychoactive: Depressant
Effects
Sedation
Motor Impairment
Respiratory Depression
Constipation
Pupil Constriction
Itchiness
Reduced Anxiety
Euphoria
Anxiety Suppression
Dulled Perception
Routes of Administration
No route information available yet.
Harm Reduction
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Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Normorphine - Даведнік па рэчыве DrugsPRO
Normorphine: Normorphine is an opiate analogue, the N-demethylated derivative of morphine, that was first described in the 1950s when a large group of N-substituted morphine analogues were characterized for activity. The compound has relatively little opioid activity in its own right, but is a usefu
