2-MPPP (2-methyl-1-phenyl-3-(piperidin-1-yl)propan-1-one) is a little-studied research chemical first reported in 2014-2015. No formal toxicology or pharmacokinetic data exist. Users describe short-lived, 'clean' mental stimulation with mild euphoria, minimal peripheral push, and a relatively soft comedown. Neurotoxicity, cardiotoxicity, and long-term health effects are unknown; treat with the same caution as any novel cathinone-like stimulant. Use accurate scales (±1 mg), start low, stay hydrated, avoid redosing more than once per 4-6 hours, and monitor blood pressure and heart rate.
Also known as: N-piperidinecathinone
Classification
Chemical: Cathinone
Psychoactive: Stimulant
Tag: Habit-Forming
Tag: Β-keto phenylpiperidine
Tag: Research-Chemical
Tag: Tentative
Effects
Mental Stimulationalertness
Bruxism And Jaw Tension
Mild Vasoconstriction
Sweating
Tachycardia And Elevated Blood Pressure
Insomnia
Euphoria
Mood Elevation
Increased Sociability And Talkativeness
Motivation Enhancement
Anxiety Or Irritability On Comedown
Increased Sociability
Music Appreciation Enhancement
Appetite Suppression
Increased Sexuality
Visual And Auditory Hallucinations
Increased Music Appreciation
Open Eye Visuals
Routes of Administration
Oral
Dosage
Threshold: 15 mg
Light: 25-50 mg
Common: 50-100 mg
Strong: 100-150 mg
Heavy: 150 mg +
Duration
Onset: 0.33-0.5 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 1-12 h
Insufflated
Dosage
Threshold: 10 mg
Light: 15-30 mg
Common: 30-60 mg
Strong: 60-110 mg
Heavy: 110 mg +
Duration
Onset: 0.05-0.12 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 1-12 h
Rectal
Dosage
Threshold: 10 mg
Light: 20-40 mg
Common: 40-80 mg
Strong: 80-120 mg
Heavy: 120 mg +
Duration
Onset: 0.03-0.08 h
Peak: 0.5-1.5 h
Offset: 1-2 h
After Effects: 1-12 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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2-MPPP - DrugsPRO anyag útmutató
2-MPPP: 2-MPPP (2-methyl-1-phenyl-3-(piperidin-1-yl)propan-1-one) is a little-studied research chemical first reported in 2014-2015. No formal toxicology or pharmacokinetic data exist. Users describe short-lived, 'clean' mental stimulation with mild euphoria, minimal peripheral push, and a relativel
