Library
4-CMA
4-CMA is a prodrug that metabolizes to 4-Chloroamphetamine (4-CA), which selectively destroys serotonergic axon terminals. Lasting mood, cognitive and sleep disturbances have been reported after single exposures. Tablets seized in Europe contained 25-150 mg active drug. No recognized medical use exists and quality-control is absent. Strongly discouraged for use due to severe neurotoxic properties.
Also known as: P-cma, Para-cma, Ro 4-6861, Para-Chloromethamphetamine, P-Chloromethamphetamine, N-methyl-4-chloroamphetamine
Classification
- Chemical: Amphetamine
- Psychoactive: Entactogen
- Psychoactive: Stimulant
- Tag: Neurotoxic
- Tag: Research-Chemical
Effects
- Stimulation
- Temperature Regulation Suppression
- Teeth Grinding
- Physical Euphoria
- Insomnia
- Jaw Tension
- Cognitive Euphoria
- Anxiety
- Wakefulness
- Motivation Suppression
- Thought Deceleration
- Depression
- Light Sensitivity
- Appetite Suppression
- Increased Libido
- Dehydration
- Open Eye Visuals
Routes of Administration
Oral
Dosage
- Threshold: ~5 mg (allergy test only; not a safety guarantee)
- Light: 5-15 mg
- Common: 15-30 mg
- Strong: 30–45 mg (not recommended)
- Heavy: 45 mg+ (strongly discouraged)
Duration
- Onset: 0.33-1 h
- Peak: 1-3 h
- Offset: 2-4 h
- After Effects: 2-24 h
- Total Duration: 3-7 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
This static page is intended as a readable non-JS and prerender-friendly library export.
