PMA is extremely dangerous and notorious for its high toxicity and risk of fatal overdose at doses only slightly above the common range. It is often mis-sold as MDMA or ecstasy but is significantly more toxic, causing hyperthermia, hypertension, and serotonin syndrome. PMA has a slower onset than MDMA (30-60 minutes vs 20-40 minutes), leading users to redose before effects are felt, resulting in accidental overdose. Deaths have occurred at doses as low as 60-80 mg. PMA is 5-10 times more potent than MDMA and acts as both a serotonin releaser and MAO-A inhibitor.
PMA molecular structure diagram from the DrugsPRO substance library.
Also known as: 4-ma, Death, 4-meoa, Killer, 4-meoma, Para-methoxyamphetamine, 4-methoxyamphetamine
Classification
Chemical: Amphetamine
Chemical: Phenethylamine
Psychoactive: Entactogen
Psychoactive: Psychedelic
Psychoactive: Stimulant
Tag: Extremely dangerous
Tag: Hallucinogen
Tag: Research-Chemical
Tag: Substituted amphetamine
Tag: Tentative
Effects
Stimulation
Abnormal Heartbeat
Increased Bodily Temperature
Increased Blood Pressure
Increased Heart Rate
Increased Perspiration
Dizziness
Anxiety
Time Distortion
Wakefulness
Empathy Enhancement
Apprehension
Appetite Suppression
Dehydration
Vibrating Vision
Cognitive Dysphoria
Visual Drifting
Open Eye Visuals
Routes of Administration
Oral
Dosage
Threshold: 5-10 mg
Light: 10-20 mg
Common: 100-120 mg
Strong: 120 mg
Heavy: 120 mg
Duration
Onset: 0.75-1.5 h
Comeup: 1-2 h
Peak: 2-5 h
Offset: 6-14 h
After Effects: 12-24 h
Total Duration: 6-24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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PMA - DrugsPRO anyag útmutató
PMA: PMA is extremely dangerous and notorious for its high toxicity and risk of fatal overdose at doses only slightly above the common range. It is often mis-sold as MDMA or ecstasy but is significantly more toxic, causing hyperthermia, hypertension, and serotonin syndrome. PMA has a slower onset th
