Static Library Class
Depressant
Depressant substances in the DrugsPRO library. Browse static substance pages, summaries and related harm reduction context without JavaScript.
Substances In This Class
These static substance pages were matched from the shared DrugsPRO library dataset used for prerender and no-JS delivery.
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lamotrigine
Self-reports cluster around four oral bands: a perceptible threshold cognitive lift at 12.5-25 mg, functional mood balance between 50-150 m…
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lean
Lean, also called purple drank or sizzurp, is a non-standard mixture usually made from codeine and promethazine cough syrup. Codeine is an…
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levomethorphan
Levomethorphan is a potent opioid analgesic that has never been marketed pharmaceutically. It is the L-stereoisomer of racemethorphan and a…
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lofentanil
Due to a sub-microgram active range, ordinary analytical balances cannot measure a non-lethal dose; volumetric dilution under inert atmosph…
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loprazolam
Is an Imidazolobenzidazepine derivative that has all the classic benzodiazepine effects. Is usually only prescribed for a short amount of t…
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lorazepam
Lorazepam is a short-acting depressant of the benzodiazepine class. First marketed by Wyeth Pharmaceuticals in the United States in 1977, i…
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lormetazepam
Relatively rare prescription benzodiazepine. Short acting with a short half life. Generally only seen in the Netherlands. Sedative, hypnoti…
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lurasidone
Lurasidone, sold under the brand name Latuda among others, is an atypical antipsychotic medication used to treat schizophrenia and bipolar…
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mam
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mebroqualone
A short acting analogue of Methaqualone, that is much more potent.
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meclonazepam
Meclonazepam is a benzodiazepine derivative structurally related to clonazepam, first developed by Hoffmann-La Roche during the 1960s. It w…
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mecloqualone
Mecloqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone that was first made in 1960 and marketed mainly in Franc…
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medazepam
Medazepam is a long-acting benzodiazepine prodrug that metabolizes to diazepam and nordazepam, producing prolonged anxiolytic and sedative…
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medetomidine
Medetomidine is a veterinary anesthetic medication with potent sedative effects. As of December 2025, it is an emerging illicit drug adulte…
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mephenaqualone
Mephenaqualone is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. It is an analo…
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meprobamate
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic…
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metaclazepam
A benzodiazepine derivative. Which is mostly an anxiolytic substance, without strong hypnotic properties that most benzodiazepines have. It…
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metaqualone
Methaqualone (brand name Quaalude in the US and Mandrax in the UK) is a central nervous system (CNS) depressant of the quinazolinone class…
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metaxalone
Metaxalone is a centrally acting skeletal-muscle relaxant, used to relieve pain and discomfort caused by muscle injuries.
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methadone
Methadone (sold under trade names such as Dolophine and Methadose) is a synthetic opioid analgesic used for the treatment of moderate to se…
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