2-Bromomescalina

2-Bromomescaline, also known as 2-bromo-3,4,5-trimethoxyphenethylamine, is a putative psychedelic drug of the scaline family and derivative of the phenethylamine hallucinogen mescaline which has an unusual 2-bromo substitution. It is an agonist for serotonin receptors, with a binding affinity of 215 nM at 5-HT1A, 513 nM at 5-HT2A and 379 nM at 5-HT2C, so while it is around 10 times more tightly binding than mescaline at 5-HT1A and 5-HT2A receptors, it is over 20 times more potent at 5-HT2C. The drug was 5-fold more potent in substituting for LSD than mescaline in rats. It is not known to have been tested in humans. 2-Bromomescaline was first described in the scientific literature, as a chemical intermediate, in 1972. It has been reported as a designer drug, first identified in Austria in January 2023. The drug is not a controlled substance in Canada as of 2025.

Also known as: 2-Bromo-Mescaline

Classification

Chemical: Phenethylamine
Psychoactive: Psychedelic

Effects

Dilated Pupils
Stimulation
Introspection
Euphoria
Visual Distortion
Color Enhancement

Routes of Administration

No route information available yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

wikipedia.org

Links

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