Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.
Clometiazolo molecular structure diagram from the DrugsPRO substance library.
Classification
Chemical: Medicine
Psychoactive: Depressant
Tag: Habit-Forming
Tag: Research-Chemical
Tag: Tentative
Effects
Anxiolytic
Sedative
Muscle Relaxation
Dystaxia
Hypnotic
Sedation
Amnesia
Reduced Anxiety
Anxiety Suppression
Dulled Perception
Routes of Administration
Oral
Dosage
Common: 150-200 mg
Heavy: 200 mg
Light: 100-150 mg
Threshold: 100 mg
Duration
No data available for this section yet.
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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Clomethiazole - Guida alle sostanze DrugsPRO
Clomethiazole: Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment fo