Cannabis is a genus of flowering plant that has been used for thousands of years for medicinal, spiritual, and recreational purposes. Its primary psychoactive constituent is delta-9-tetrahydrocannabinol (THC), though dozens of additional cannabinoids and terpenes contribute to its overall effects. It ranks among the most widely consumed recreational substances globally, behind only alcohol, caffeine, and tobacco. Its two principal species, sativa and indica, are recognized for producing distinct effect profiles.
THC molecular structure diagram from the DrugsPRO substance library.
Also known as: Dronabinol, Tetrahydrocannabinol
Classification
Chemical: Cannabinoid
Chemical: Medicine
Tag: Common
Tag: Habit-Forming
Effects
Laughter
Spontaneous Tactile Sensations
Sedation
Nausea Suppression
Vasodilation
Pain Relief
Paranoia
Dream Suppression
Thought Connectivity
Thought Deceleration
Immersion Enhancement
Conceptual Thinking
Appetite Enhancement
Changes In Gravity
Dehydration
Synaesthesia
Color Enhancement
Acuity Suppression
Routes of Administration
Oral
Dosage
Heavy: 25 mg
Light: 1 – 5 mg
Common: 5 – 10 mg
Strong: 10 – 25 mg
Threshold: 1 mg
Duration
Onset: 0.33-1 h
Comeup: 0.5-1 h
Peak: 1-2 h
Offset: 4-6 h
After Effects: 6-12 h
Smoked
Dosage
Heavy: 100 mg
Light: 0.4 – 2 mg
Common: 2 – 4 mg
Strong: 60-100 mg
Threshold: 0.4 mg
Duration
Onset: 0-0.17 h
Comeup: 0.1-0.2 h
Peak: 0.25-0.75 h
Offset: 3-4 h
After Effects: 0.8-3 h
Sublingual
Dosage
No data available for this section yet.
Duration
Onset: 0-0.2 h
Comeup: 0.2-0.5 h
Peak: 0.5-1 h
Offset: 4-6 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
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THC - Guida alle sostanze DrugsPRO
THC: Cannabis is a genus of flowering plant that has been used for thousands of years for medicinal, spiritual, and recreational purposes. Its primary psychoactive constituent is delta-9-tetrahydrocannabinol (THC), though dozens of additional cannabinoids and terpenes contribute to its overall effec
