Propranolol

Propranolol is a non-selective beta-adrenergic antagonist and naphthalene derivative first approved by the FDA in 1967. It is prescribed for a broad range of conditions including hypertension, essential tremor, migraine prophylaxis, and anxiety. As a racemic mixture, its S(-)-enantiomer demonstrates roughly 100 times greater binding affinity for beta-adrenergic receptors than its counterpart, accounting for most of its pharmacological activity.

Also known as: Sumial, Ciplar, Inderal, Deralin, Dociton, Inderal LA, Innopran XL, Hemangeol, Hemangiol

Classification

Chemical: Medicine
Psychoactive: Depressant
Tag: Anxiolytic
Tag: Beta-adrenergic antagonist
Tag: Common
Tag: Naphthalene derivative
Tag: Pharmaceutical

Effects

Decreased Heart Rate
Decreased Blood Pressure
Sedation
Reduced Heart Rate
Lowered Blood Pressure
Tremor
Anxiety Suppression
Dream Potentiation
Dizziness
Anxiety
Vivid Dreams
Sadness

Routes of Administration

Oral

Dosage

Heavy: 160+ mg
Light: 10 – 30 mg
Common: 30 – 80 mg
Strong: 80 – 140 mg
Threshold: 10 mg

Duration

Onset: 0.17-0.75 h
After Effects: 1-8 h
Peak: 1-4 h
Offset: 6-12 h
Total Duration: 6-12 h

Intravenous

Dosage

Heavy: 20+ mg
Light: 1-2 mg
Common: 2-10 mg
Strong: 10-20 mg
Threshold: 1 mg

Duration

No data available for this section yet.

Harm Reduction

Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.

Sources

Substance data is aggregated from the following public harm-reduction and reference sources.

Links

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