Library
SAM-e
S-Adenosyl-L-methionine (also called S-Adenosyl methionine, Ademethionine and commonly as SAMe and SAM-e) is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation in biological organisms. SAMe is an amino acid methionine bound to an ATP molecule that circulates in the blood naturally and acts as a 'methyl donor'. A methyl group in chemistry is simply a carbon molecule (bound to some hydrogens), and donating a methyl group to other molecules can accelerate or preserve reactions in the body as a form of metabolic 'maintenance'.[citation needed].
Also known as: Adomet, Ademetionine, S-adenosyl methionine
Classification
- Chemical: Medicine
- Psychoactive: Nootropic
- Tag: Cognitive-enhancer
- Tag: Mood-enhancer
- Tag: Nitrogenous organic acid
- Tag: Supplement
Effects
- Stimulation
- Pain Relief
- Stamina Enhancement
- Motivation Enhancement
- Thought Organization
- Memory Enhancement
- Cognitive Euphoria
- Analysis Enhancement
- Thought Connectivity
- Bodily Control Enhancement
- Appetite Suppression
Routes of Administration
Oral
Dosage
- Threshold: 200 mg
- Light: 400-800 mg
- Common: 800-1200 mg
- Strong: 1200-1600 mg
- Heavy: 1600 mg
Duration
- Onset: 1.67-3 h
- Peak: 4-6 h
- Offset: 2-4 h
- After Effects: 24 h
Harm Reduction
Check interactions before mixing substances, pay attention to dose spacing and hydration, and treat all dosage guidance as approximate rather than guaranteed safe.
Sources
Substance data is aggregated from the following public harm-reduction and reference sources.
Links
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