Drug Purity Report Week 33, 2026

DrugsPRO sample 20260810AUsV9

Drug Purity Report #33/26. Welcome to “last week on drugs”, a new blog post series by PRO Test dedicated to reporting on drug market purity. Since last week we have seen doppleganger Ecstasy pills, pills with more than 1 stimulant, and a continued diversity among cathinone samples. 

Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.

  • Doppleganger Ecstasy pills
    • Every pill should always be considered as different, as illustrated by most recent red TikTok and blue Punisher pills found in Austria. With half of the samples containing MDMA, and the other half caffeine, the risk of possible overdose increases exponentially. A weak effect (caffeine pill) can encourage person using it to ingest more and overestimate their tolerance.
  • Multi-stimulant pills
    • Pills with both MDMA and caffeine were found in Austria, yet another kind of blue Punisher pressies. MDMA with amphetamine was found in a round orange pill in Innsbruck, and a Donkey Kong pill with NEP mixed with unknown compound was found in Slovenia, after recent detections in other countries throughout the region. 
  • Cathinone diversity
    • As reported in the previous weeks, 4-MMC is increasingly rare and replacements are still all over the place. Those include from 3-CMC, 4-CMC, 2-MMC, 3-MMC, 4-BMC, NEP, with also Ethylpentylone, also known as ephylone or bk-EBDP, found this week.

Last Week at a Glance

  • 206 samples from 6 countries (Austria, France, Germany, Slovenia, Spain and Switzerland) were included this week.
  • 161 samples contained a quantified result, including 67 pills and 5 LSD samples.
  • 83 samples contained more than one detected ingredient.
  • LSD median purity/content is 164µg, compared with 69µg in the yearly reference period.

Key Purity Differences

  • LSD median purity/content is 164µg, compared with 69µg in the yearly reference period.
  • Amphetamine median purity/content is 10%, compared with 38% in the yearly reference period.
  • Mephedrone median purity/content is 63%, compared with 88% in the yearly reference period.

Purity and Content

Median quantified results for 10–16 August 2026. The yearly reference is shown in parentheses where sufficient comparison data is available.

Samples Substance Typical purity / content
54 MDMA 152.5mg (160mg*)
Middle 50%: 126.3–184.3mg
30 Cocaine 65% (86%*)
Middle 50%: 31–75.5%
9 Amphetamine 10% (38%*)
Middle 50%: 7–55%
9 Ketamine 92% (95%*)
Middle 50%: 36–96%
9 Mephedrone 63% (88%*)
Middle 50%: 48–88%
6 2C substances 15mg (12mg*)
Middle 50%: 7.5–15.8mg
5 LSD 164µg (69µg*)
Middle 50%: 65–180µg

How to read this: Bold = this week’s median (typical) result; “Middle 50%” = half of the results; (*) = median from the last 365 days; ▲/▼ = higher/lower than last week.

Most Common Adulterants and Other Impurities

Across the last 365 days, 1,663 mixed samples contained 127 distinct additional ingredients.

Samples Additional ingredient Share of substance mixtures Most often found with
573 Caffeine 84.8%
of amphetamine samples
Amphetamine, Heroin, MDMA
218 Unknown 21.3%
of MDMA samples
MDMA, Mephedrone, 2C substances
148 Paracetamol 82.3%
of heroin samples
Heroin, Cocaine, Ketamine
114 iso-LSD 95%
of LSD samples
LSD
99 MDMA 46.2%
of ketamine samples
Ketamine, 2C substances, Mephedrone
98 4-CMC 38.1%
of mephedrone samples
Mephedrone, MDMA, Ketamine
89 Procaine 35.1%
of cocaine samples
Cocaine, Ketamine, MDMA
88 Ketamine 19.2%
of MDMA samples
MDMA, Amphetamine, 2C substances
62 2-MMC 15.3%
of mephedrone samples
Mephedrone, MDMA, Ketamine
58 Phenacetin 17.2%
of cocaine samples
Cocaine, Heroin, Ketamine
44 Levamisole 18%
of cocaine samples
Cocaine, Ketamine
38 4-BEC 21.6%
of mephedrone samples
Mephedrone
36 2C-B 10.1%
of MDMA samples
MDMA, Ketamine, Amphetamine
36 Cocaine 12.6%
of ketamine samples
Ketamine, Heroin, MDMA
34 Amphetamine 14.3%
of ketamine samples
Ketamine, MDMA, Cocaine
31 DPIA 9.1%
of amphetamine samples
Amphetamine
29 4-MMC 6.3%
of MDMA samples
MDMA, Ketamine, Cocaine
24 1-PEA 6.7%
of amphetamine samples
Amphetamine, MDMA
20 NEP 5.7%
of mephedrone samples
Mephedrone, MDMA, Ketamine
17 Tetramisole 7.1%
of cocaine samples
Cocaine

▲/▼ shows whether its share in the rolling 365-day data increased or decreased since last week. No arrow means no change or no comparison.

Impurities Detected This Week

MDMA: 2C-B (2), 4-MMC (2), Amphetamine (1), Caffeine (4), DMXE (2), Ketamine (2), N- (2), Unknown (2)

Amphetamine: 1-PEA (2), Caffeine (30), Cocaine (4), DPIA (2), MDMA (1), Unknown (1)

Cocaine: Amphetamine (4), Caffeine (8), Ketamine (2), Levamisole (12), Lidocaine (2), Phenacetin (4), Procaine (6), Unknown (1)

Ketamine: 2C-B (2), Cocaine (2), MDMA (2), Phenacetin (2)

2C substances: Ketamine (2), L-Glutamine (1), MDMA (2), Unknown (2)

LSD: iso-LSD (2)

Mephedrone: MDMA (2), NEP (2), Other (3)

Heroin: Caffeine (1), Unknown (1)

Remaining detected substances: 2-MMC (7), 3-CMC (6), 3-Me-PCP (1), 4-BMC (1), 4-CMC (17), aMT (2), Caffeine (6), Deschloro-N-Ethylketamin (2), Ethylpentedron (2), GHB (2), Levamisole (2), NEP (5), No Psychoactive Substance Detected (2), Paracetamol (1), Procaine (3), Tapentadol (1), Unknown (7)

Data Sources

This report is based on drug-checking data published by: (Bern, (Lausanne) École des sciences criminelles (ESC), (Luzern, (Zürich) Reseachem GmbH, addiction-neuchatel.ch, Basel) IRM Basel, Biel) Pharmazeutischen Kontrolllabor Bern, checkit.wien, contact-suchthilfe.ch, DIZ / Saferparty, drogart.org, drogenarbeitz6.at, drugchecking.berlin, drugchecking.ch, druglab.fr, energycontrol.org, knowyourstuff.nz, nightlifevaud.ch, nuit-blanche.ch, raveitsafe.ch, saferdancebasel.ch, saferparty.ch, tragwerk-luzern.ch, Trimbos, Université Lausanne, wedinos.wales.

All of this data is available at your fingertips in the DrugsPRO app for Android, iOS, and the web.

Drug-checking results describe tested samples only and are not representative of the entire market.

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