Drug Purity Report Week 33, 2026

Drug Purity Report #33/26. Welcome to “last week on drugs”, a new blog post series by PRO Test dedicated to reporting on drug market purity. Since last week we have seen doppleganger Ecstasy pills, pills with more than 1 stimulant, and a continued diversity among cathinone samples.

Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.

Doppleganger Ecstasy pills
- Every pill should always be considered as different, as illustrated by most recent red TikTok and blue Punisher pills found in Austria. With half of the samples containing MDMA, and the other half caffeine, the risk of possible overdose increases exponentially. A weak effect (caffeine pill) can encourage person using it to ingest more and overestimate their tolerance.
Multi-stimulant pills
- Pills with both MDMA and caffeine were found in Austria, yet another kind of blue Punisher pressies. MDMA with amphetamine was found in a round orange pill in Innsbruck, and a Donkey Kong pill with NEP mixed with unknown compound was found in Slovenia, after recent detections in other countries throughout the region.
Cathinone diversity
- As reported in the previous weeks, 4-MMC is increasingly rare and replacements are still all over the place. Those include from 3-CMC, 4-CMC, 2-MMC, 3-MMC, 4-BMC, and NEP, also reported by the Austrian lab as ethylpentedron, found this week.

Last Week at a Glance

217 samples from 6 countries (Austria, France, Germany, Slovenia, Spain and Switzerland) were included this week.
172 samples contained a quantified result, including 73 pills and 6 LSD samples.
89 samples contained more than one detected ingredient.
LSD median purity/content is 172µg, compared with 69µg in the yearly reference period.

Key Purity Differences

LSD median purity/content is 172µg, compared with 69µg in the yearly reference period.
Amphetamine median purity/content is 10%, compared with 38% in the yearly reference period.
Cocaine median purity/content is 65%, compared with 86% in the yearly reference period.

Purity and Content

Median quantified results for 10–16 August 2026. The yearly reference is shown in parentheses where sufficient comparison data is available.

Samples	Substance	Typical purity / content
58	MDMA	*154mg (160mg)** Middle 50%: 131.5–191.3mg ▼
30	Cocaine	*65% (86%)** Middle 50%: 31–75.5% ▼
10	Mephedrone	*69.5% (88%)** Middle 50%: 48–88% ▼
9	Amphetamine	*10% (38%)** Middle 50%: 7–55%
9	Ketamine	*92% (95%)** Middle 50%: 36–96%
7	2C substances	*15mg (12mg)** Middle 50%: 10–16.5mg ▲
6	LSD	*172µg (69µg)** Middle 50%: 89.8–180µg ▲

How to read this: Bold = this week’s median (typical) result; “Middle 50%” = half of the results; (*) = median from the last 365 days; ▲/▼ = higher/lower than last week.

Most Common Adulterants and Other Impurities

Across the last 365 days, 1,671 mixed samples contained 123 distinct additional ingredients.

Samples	Additional ingredient	Share of substance mixtures	Most often found with
573	Caffeine	84.8% ▲ of amphetamine samples	Amphetamine, Heroin, MDMA
218	Unknown	21.3% ▲ of MDMA samples	MDMA, Mephedrone, 2C substances
148	Paracetamol	82.8% of heroin samples	Heroin, Cocaine, Ketamine
114	iso-LSD	95% ▲ of LSD samples	LSD
99	MDMA	46.2% of ketamine samples	Ketamine, 2C substances, Mephedrone
98	4-CMC	38.1% ▼ of mephedrone samples	Mephedrone, MDMA, Ketamine
89	Procaine	35.1% ▲ of cocaine samples	Cocaine, Ketamine, MDMA
88	Ketamine	19.2% ▲ of MDMA samples	MDMA, Amphetamine, 2C substances
62	2-MMC	15.3% ▼ of mephedrone samples	Mephedrone, MDMA, Ketamine
58	Phenacetin	17.2% ▼ of cocaine samples	Cocaine, Heroin, Ketamine
44	Levamisole	18% ▼ of cocaine samples	Cocaine, Ketamine
38	4-BEC	21.6% ▼ of mephedrone samples	Mephedrone
36	2C-B	10.1% ▲ of MDMA samples	MDMA, Ketamine, Amphetamine
36	Cocaine	12.6% of ketamine samples	Ketamine, Heroin, MDMA
34	Amphetamine	14.3% ▼ of ketamine samples	Ketamine, MDMA, Cocaine
31	DPIA	9.1% ▲ of amphetamine samples	Amphetamine
29	4-MMC	6.3% ▲ of MDMA samples	MDMA, Ketamine, Cocaine
27	d-8-Tetrahydrocannabinol	32.5% ▼ of THC samples	THC/cannabinoids
24	1-PEA	6.7% ▲ of amphetamine samples	Amphetamine, MDMA
20	NEP	5.7% ▼ of mephedrone samples	Mephedrone, MDMA, Ketamine

▲/▼ shows whether its share in the rolling 365-day data increased or decreased since last week. No arrow means no change or no comparison.

Impurities Detected This Week

MDMA: 2C-B (2), 4-CMC (1), 4-MMC (2), Amphetamine (1), Caffeine (5), DMXE (2), Ketamine (2), N- (2), Unknown (2)

Amphetamine: 1-PEA (2), Caffeine (30), Cocaine (4), DPIA (2), MDMA (1), Unknown (1)

Cocaine: Amphetamine (4), Caffeine (8), Ketamine (2), Levamisole (12), Lidocaine (2), Phenacetin (4), Procaine (6), Unknown (1)

Ketamine: 2C-B (2), Cocaine (2), MDMA (2), Phenacetin (2)

2C substances: Ketamine (2), L-Glutamine (1), MDMA (2), Unknown (2)

LSD: iso-LSD (3)

Mephedrone: Creatin (1), MDMA (2), N- (2), NEP (2), Unknown (1)

Heroin: Caffeine (1), Unknown (1)

Remaining detected substances: 2-MMC (7), 3-CMC (6), 3-Me-PCP (1), 4-BMC (1), 4-CMC (18), aMT (2), Caffeine (6), GHB (2), Levamisole (2), NEP (8), No Psychoactive Substance Detected (2), O-PCE (2), Paracetamol (1), Procaine (4), Tapentadol (1), Unknown (9)