Drug Purity Report Week 41, 2026

Drug Purity Report: Week 41, 2026

This article has been translated to English.

Drug Purity Report #41/26. Welcome to “last week on drugs”, the series by PRO Test that brings you fresh drug purity news from the clandestine market. PMMA, one of extremely dangerous MDMA (Ecstasy, Molly) adulterants continues to be found in European pils, among cathinones and even at least one piperazine. Synthetic cannabinoids market diversity is expanding as well, with ADB-HEXINACA making the first public appearance in available data.

Available lab results originate mostly in Western Europe, but the detected patterns are likely to have a much wider reach. Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.

PMMA, one of most dangerous MDMA adulterants, is still around. Recently confirmed (again) in pills with logos Trump, Club 555 and Gorilla in Austria, Belgium and Netherlands, PMMA remains to be a Europe-wide issue. Not only is this compound unlikely to cause any desirable effects, it might confuser user into ingesting more, amplifying the significant risk of overdose, specifically serotonin syndrome. While less dangerous than closely related PMA, PMMA is not only enough of a concern for UNODC to issue an alert, but also is being found deliberately mixed with MDMA making detection harder.

New synthetic cannabinoid makes an appearance – ADB-HEXINACA. Another strong cannabinoid receptor agonist joins the ranks of the plethora of synthetics sprayed onto cheap CBD flowers. With hemp being nowadays hard to visually tell apart from regular recreational cannabis flowers, the incentive to adulterate remains high for dishonest dealers. Both fully synthetics, like HEXINACA, PINACA, CHMINACA class compounds, as well as semi-synthetics like HHC, HHCP, d8-THC, continue to be confirmed in multiple countries. The stronger synthetics, like HEXINACA, pose significant risks for cannabinoids, including acute kidney injury with prolonged dose. 

Scam of the Week

Samples that were not what they were sold as. Substitutions like these can be picked up with a test kit before anything is taken.

Sold as Actually Samples
MDMA PMMA 2 samples
MDMA Methamphetamine 1 sample
Mescalin no active substance 1 sample

Dishonourable mentions from this week. What the lab actually found, with the date and the place it was checked.

What was in it Sold as When Where
Caffeine 189mg MDMA 5 October Vienna, Austria
Caffeine 172mg MDMA 5 October Vienna, Austria
Cannabis, MDMB-PINACA, ADB-HEXINACA THC-Cannabis 5 October Vienna, Austria

[Additional dishonourable mentions. Name the individual samples worth calling out, each with the date and the place in brackets. Leave it out when the table says enough.]

Last Week at a Glance

  • 133 samples from 7 countries (Australia, Austria, Germany, Netherlands, Slovenia, Spain and Switzerland) were included this week.
  • 104 samples contained a quantified result, including 44 pills and 3 LSD samples.
  • 61 samples contained more than one detected ingredient.
  • Amphetamine was typically 8.1% this week, against 57% across the twelve months before.

What People Searched For

Below is a list of substances people are searching for in the DrugsPRO app when coming from Google, ordered by how often they were searched over the past week. Something suddenly on the rise can stand out in search interest before it shows up in lab results.

# Substance Trend
1 Ethylbromazolam rising
2 NEP steady
3 Bromonordiazepam cooling
4 Flubrotizolam steady
5 4-Pro-MET rising
6 1Fe-LSD cooling
7 MDPHP cooling
8 4-Pro-MET rising
9 Ethylflualprazolam cooling
10 4-CMC rising

Substances in Focus

Three substances covered in more detail this week: what they are, and how they are dosed and how long they last by route of administration. Doses and durations come from the DrugsPRO library and describe the substance itself, not any tested sample.

PMMA

PMMA, para-methoxymethylamphetamine, is a structural hybrid of PMA and methamphetamine that is sold as ecstasy, historically under logos such as Mitsubishi and Jumbo. Read more on euda.europa.eu

Oral

No dose range is shown for this substance. There is no dose that makes it safe, and drug-checking services advise against taking it at all.

MCPP

meta-Chlorophenylpiperazine (also known as mCPP) is a stimulant drug of the phenylpiperazine class. It was first synthesized as one in a series of potential novel antihistamines by Thomas H. Wicker Jr. in 1951 as part of his doctoral work at the University of Florida. Read more on psychonautwiki.org

Oral

Dose range

15 mg20-50 mg50-120 mg120-150 mg150 mg
 
ThresholdLightCommonStrongHeavy

Duration

Onset 0.3-1 hCome-up 0.3-1 hPeak 2-4 hOffset 3-8 h

Source: psychonautwiki.org

MDMA

MDMA is a classical entactogen of the substituted amphetamine class, first developed in 1912 by the pharmaceutical company Merck. It remained largely obscure until the 1970s, when it gained recognition in underground psychotherapy circles before spreading into nightlife and rave culture. Read more on dose.wiki

Source: erowid.org, tripsit.me, psychonautwiki.org

Oral

Dose range

35 mg35 – 75 mg75 – 125 mg125 – 175 mg175+ mg
 
ThresholdLightCommonStrongHeavy

Duration

Onset 0.33-1.17 hCome-up 0.5-1 hPeak 1.5-2.5 hOffset 1-1.5 h

Total: 4-6 h. After effects: 12-48 h.

Insufflated

Dose range

5 mg30-70 mg70-120 mg120-165 mg165+ mg
 
ThresholdLightCommonStrongHeavy

Duration

Onset 0.03-0.25 hPeak 1-2.5 hOffset 2.5-5 h

Total: 3-5 h. After effects: 12-36 h.

Rectal

Dose range

30-70 mg70-120 mg120-165 mg165 mg
 
LightCommonStrongHeavy

Source: dose.wiki, tripsit.me, psychonautwiki.org, substance.wiki

Bars are drawn to the same scale within a substance. An open-ended band such as “175+ mg” is shown reaching the end of the scale.

Purity and Content

Below, the big number in each row is the typical result for 5–11 October 2026: half the samples came in stronger, half weaker. The smaller one in brackets is the same thing measured over the last twelve months.

Samples Substance Typical purity / content
10 Cocaine 61% (88%*)
half of samples 32.2 to 74.7%
10 MDMA 129.5mg (157mg*)
half of samples 109.5 to 167.3mg
7 Mephedrone 59.2% (85%*)
half of samples 29.9 to 67.1%
6 Amphetamine 8.1% (57%*)
half of samples 2.5 to 53.3%

* the 12 months before this week, not the same week a year ago

Most Common Adulterants and Other Impurities

Across the last 365 days, 1,977 mixed samples contained 216 distinct additional ingredients.

Samples Additional ingredient Share of substance mixtures Most often found with
691 Caffeine 85.1%
of amphetamine samples · higher than last week
Amphetamine, Heroin, MDMA
276 Unknown 22.9%
of MDMA samples · lower than last week
MDMA, Mephedrone, 2C substances
156 Paracetamol 80.5%
of heroin samples · lower than last week
Heroin, Cocaine, Ketamine
113 MDMA 43.8%
of ketamine samples · higher than last week
Ketamine, 2C substances, Mephedrone
110 Procaine 34.9%
of cocaine samples · higher than last week
Cocaine, Mephedrone, Ketamine
107 iso-LSD 93.9%
of LSD samples
LSD
105 4-CMC 34.5%
of mephedrone samples
Mephedrone, MDMA, Ketamine
102 Ketamine 17%
of MDMA samples · lower than last week
MDMA, Amphetamine, Cocaine
62 Phenacetin 15.8%
of cocaine samples · lower than last week
Cocaine, Heroin, Ketamine
56 Levamisole 19.4%
of cocaine samples · lower than last week
Cocaine, Ketamine
55 2-MMC 11.5%
of mephedrone samples · lower than last week
Mephedrone, Ketamine, MDMA
43 4-BEC 21.5%
of mephedrone samples · lower than last week
Mephedrone, Ketamine
42 Cocaine 12.4%
of ketamine samples · higher than last week
Ketamine, Heroin, Amphetamine
41 Amphetamine 12.4%
of ketamine samples · lower than last week
Ketamine, MDMA, Cocaine
38 2C-B 8.5%
of MDMA samples · higher than last week
MDMA, Ketamine, Amphetamine
37 4-MMC 7.1%
of MDMA samples · higher than last week
MDMA, Ketamine, Cocaine
32 1-PEA 7%
of amphetamine samples · higher than last week
Amphetamine, MDMA
29 DPIA 6.5%
of amphetamine samples · higher than last week
Amphetamine
28 d-8-Tetrahydrocannabinol 30.4%
of THC samples · higher than last week
THC/cannabinoids
26 NEP 7.5%
of mephedrone samples · higher than last week
Mephedrone, MDMA, Ketamine

Impurities Detected This Week

MDMA: 3-CMC (2), 4-BMC (1), 4-CMC (1), 4-MMC (4), Amphetamine (2), Caffeine (2), Ketamine (2), Maltodextrin (1), PMMA (1), Sildenafil (1), Theophyllin (2)

Amphetamine: 1-PEA (2), 3-CMC (1), 4-MMC (1), Caffeine (10), Cocaine (1), DPIA (3), Ketamine (1), MDMA (2), Methamphetamine (1)

Methamphetamine: Amphetamine (1)

Cocaine: Amphetamine (1), Caffeine (3), Levamisole (3), Procaine (7)

Ketamine: 3-CMC (1), 4-MMC (1), Amphetamine (1), MDMA (2)

LSD: ETH-LAD (1), iso-LSD (3), MiPLA (1), Unknown (1)

THC/cannabinoids: 5F-MDMB-PINACA (1), ADB-HEXINACA (1), d-8-Tetrahydrocannabinol (1), Delta-9-Thcp (1), Free Cbd (2), Free Thc (2), HHC (1), MDMB-PINACA (1), Nicht Näher Bestimmtes Semi- Synthetisches Cannabinoid (1), Tetrahydrocannabidiol (1), Unknown (3)

Mephedrone: 3-CMC (2), 4-BEC (2), 4-CMC (2), A-PVP (1), Amphetamine (1), Ketamine (1), MDMA (4), Unknown (3)

Remaining detected substances: 2-MMC (4), 3-CMC (2), 4-BMC (1), 4-CMC (12), 5-Dimethoxy-Benzeenethanamine (1), Alprazolam (1), Caffeine (3), Cyproheptadine (1), MCPP (1), N-Acetyl-2-Bromo-4 (1), NEP (7), PMMA (2), Unknown (4)

Data Sources

This report is based on drug-checking data published by: addiction-neuchatel.ch, ailaket.com, BAONPS, CanTEST, checkit.wien, contact-suchthilfe.ch, DILU, drogart.org, drogenarbeitz6.at, drugchecking.berlin, drugchecking.ch, druglab.fr, DrugsData, École des sciences criminelles (ESC), energycontrol.org, eurotox.org, IRM Basel, knowyourstuff.nz, modusvivendi-be.org, neutravel.net, nightlifevaud.ch, NSW Health, nuit-blanche.ch, Pharmazeutischen Kontrolllabor Bern, Pill Testing Australia, raveitsafe.ch, Reseachem GmbH, saferdancebasel.ch, SaferParty.ch, stoftest.org, toxibot.com, tragwerk-luzern.ch, Trimbos, triptalks.at, Université Lausanne, Victorian Department of Health, Victorian Pill Testing Service, wedinos.wales.

All of this data is available at your fingertips in the DrugsPRO app for Android, iOS, and the web.

Drug-checking results describe tested samples only and are not representative of the entire market.

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No test result can tell you a substance is safe. No substance is 100% safe.This article is published for harm reduction purposes. It does not encourage the use of psychoactive substances and does not replace medical advice.