Drug Purity Report Week 32, 2026

Drug Purity Report #32/26. Welcome to “last week on drugs”, a new blog post series by PRO Test dedicated to reporting on drug market purity. This time – another week, another PMMA pill. On top of that more novel semi-synthetic cannabinoids and other research chemicals. 

Caution: warnings are not limited to compounds mentioned in this post. All our published lab results are warnings. No substance is 100% safe.

Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.

• Donkey Kong PMMA pill in Zurich, Switzerland

Whoever has been putting out pressies (pills) with PMMA is not taking it easy. Another pill found with PMMA, and another sighting of one previously spotted. Considering the scale of European drug market and the evident cross continental spread, it’s reasonable to assume that at least several thousands PMMA pills are currently in circulation.

• Delta-8-THO in Maribor, Slovenia

The Slovenian drug checking NGO Drogart reported new semi-synthetic cannabinoids, THC butanenitrile oximes (THO). More details from Drogart:

The results of the analysis conducted at the National Laboratory for Health, Environment and Food showed that a sample of cannabis purchased as cannabis with the semi-synthetic cannabinoid tetra-9-hydrocannabinol (T9HC) in a physical store in Maribor contained two other semi-synthetic cannabinoids, delta-9-THC butanenitrile oxime (delta-9-THO) and delta-8-THC butanenitrile oxime (delta-8-THO).

Not much information is available about the substances delta-8-THO and delta-9-THOV. Users of the aforementioned semi-synthetic cannabinoids have reported intense effects, dissociation, blurred vision, nausea and loss of appetite in the past. There is currently no additional information in the literature about the effects of delta-9-THO.

Synthetic and some semi-synthetic cannabinoids are extremely potent and unpredictable substances that can cause rapid loss of consciousness, slowed or labored breathing, epileptic seizures, convulsions, frequent vomiting, agitation, delirium, psychotic episodes, aggressive behavior, chest pain, irregular heartbeat, confusion, fainting, irritability, hallucinations, paranoia, and in the most severe cases, sudden death.

• Fake Xanax in Bern, Switzerland

A fake Xanax sample resembling the classic alprazolam pill checked by Swiss experts was found to contain Flualprazolam and Meclonazepam. With those compounds being so called “research chemicals” their risk profile is unclear, however flualprazolam is known to have longer lasting effects than alprazolam. Combined with possibly unfamiliar effects the overdose risk is high. In case of benzodiazepines overdose means memory loss, likely injury or other accident, significantly increased likelihood to follow bad ideas.

Last Week at a Glance

• 83 samples from 5 countries (Austria, France, Germany, Slovenia and Switzerland) were included this week.
• 76 samples contained a quantified result, including 39 pills and 7 LSD samples.
• 18 samples contained more than one detected ingredient.
• LSD median purity/content is 80µg, compared with 69µg in the yearly reference period.

Key Purity Differences

• LSD median purity/content is 80µg, compared with 69µg in the yearly reference period.
• Cocaine median purity/content is 90%, compared with 86% in the yearly reference period.
• Mephedrone median purity/content is 84%, compared with 88% in the yearly reference period.

Purity and Content

Median quantified results for 3–9 August 2026. The yearly reference is shown in parentheses where sufficient comparison data is available.

Samples	Substance	Typical purity / content
32	MDMA	162.5mg (160mg*) Middle 50%: 136.3–189.3mg ▼
7	LSD	80µg (69µg*) Middle 50%: 66–169µg
5	2C substances	12mg (13mg*) Middle 50%: 6–15mg
3	Cocaine	90% (86%*) Middle 50%: 72–94.5% ▲
3	Mephedrone	84% (88%*) Middle 50%: 83–89% ▲

How to read this: Bold = this week’s median (typical) result; “Middle 50%” = half of the results; (*) = median from the last 365 days; ▲/▼ = higher/lower than last week.

Most Common Adulterants and Other Impurities

Across the last 365 days, 1,635 mixed samples contained 126 distinct additional ingredients.

Samples	Additional ingredient	Share of substance mixtures	Most often found with
570	Caffeine	84.7% ▼ of amphetamine samples	Amphetamine, Heroin, MDMA
214	Unknown	21.1% ▲ of MDMA samples	MDMA, Mephedrone, 2C substances
148	Paracetamol	82.3% of heroin samples	Heroin, Cocaine, Ketamine
108	iso-LSD	95.6% of LSD samples	LSD
98	4-CMC	38.5% ▲ of mephedrone samples	Mephedrone, MDMA, Ketamine
95	MDMA	45.7% ▲ of ketamine samples	Ketamine, 2C substances, Mephedrone
88	Procaine	34.9% ▲ of cocaine samples	Cocaine, Ketamine, MDMA
85	Ketamine	19% ▲ of MDMA samples	MDMA, Amphetamine, Cocaine
62	2-MMC	15.5% ▼ of mephedrone samples	Mephedrone, MDMA, Ketamine
58	Phenacetin	17.2% ▲ of cocaine samples	Cocaine, Heroin, Ketamine
44	Levamisole	18.1% ▲ of cocaine samples	Cocaine, Ketamine
38	4-BEC	21.8% ▼ of mephedrone samples	Mephedrone
36	Cocaine	12.9% ▼ of ketamine samples	Ketamine, Heroin, MDMA
33	2C-B	9.7% ▲ of MDMA samples	MDMA, Ketamine, Amphetamine
33	Amphetamine	13.8% ▲ of ketamine samples	Ketamine, MDMA, Cocaine
31	DPIA	9.1% ▲ of amphetamine samples	Amphetamine
28	4-MMC	6.1% ▼ of MDMA samples	MDMA, Ketamine, Cocaine
24	1-PEA	6.8% ▲ of amphetamine samples	Amphetamine, MDMA
19	NEP	5.7% ▲ of mephedrone samples	Mephedrone, Ketamine, MDMA
17	Tetramisole	7.1% ▼ of cocaine samples	Cocaine

▲/▼ shows whether its share in the rolling 365-day data increased or decreased since last week. No arrow means no change or no comparison.

Impurities Detected This Week

MDMA: 2C-B (2), 4-MMC (1), Ketamine (1), NEP (1)

Amphetamine: Caffeine (1), Unknown (1)

Cocaine: Caffeine (1), Procaine (1)

Ketamine: 2C-B (1), MDMA (1)

2C substances: Ketamine (1), MDMA (2), Unknown (1)

LSD: iso-LSD (3)

THC/cannabinoids: HHC (1), MDMB-PINACA (1)

Mephedrone: iso-4-MMC (1), MDMA (1)

Remaining detected substances: 2-MMC (4), 3-CMC (1), 4-BMC (1), 4-CMC (12), 4-HO-MET (1), CBG (1), Delta-8-Tho (1), Delta-9-Tho (1), Flualprazolam (1), iso-3-CMC (1), MDA (1), Meclonazepam (1), PMMA (2), Unknown (2)

Data Sources

This report is based on drug-checking data published by: (Bern, (Lausanne) École des sciences criminelles (ESC), (Luzern, (Zürich) Reseachem GmbH, addiction-neuchatel.ch, Basel) IRM Basel, Biel) Pharmazeutischen Kontrolllabor Bern, checkit.wien, contact-suchthilfe.ch, drogart.org, drogenarbeitz6.at, drugchecking.berlin, drugchecking.ch, druglab.fr, energycontrol.org, knowyourstuff.nz, nightlifevaud.ch, nuit-blanche.ch, raveitsafe.ch, saferdancebasel.ch, saferparty.ch, tragwerk-luzern.ch, Trimbos, Université Lausanne, wedinos.wales.

All of this data is available at your fingertips in the DrugsPRO app for Android, iOS, and the web.

Drug-checking results describe tested samples only and are not representative of the entire market.