Drug Purity Report Week 38, 2026
This article has been translated to English.
Drug Purity Report #38/26. Welcome to “last week on drugs”, the series by PRO Test that brings you fresh drug purity news from the clandestine market. In this week’s edition: developments regarding 3-MMC replacement, problem with underdosed pills and extremely dosed tablets.
Data fatigue is real, so here we come to give you the gist of what’s going on out there. For more details, photos, and other information on thousands of drugs, head out straight to the DrugsPRO app.
3-MMC, the replacement of 4-MMC (Mephedrone), is getting harder to find in Europe. In the past months we have recorded compounds such as most notably 4-BEC, 4-BMC, 4-CMC, 2-MMC and NEP sold as 3-MMC or 4-MMC. Researchers warn that the novel cathinones could be escaping their simplified expected pharmacological profile, therefore extra caution is advised. Lately to the creative adulterant mixtures there is a new addition: MDMA used as a cut for MMC. It makes a little sense, with both being serotonergic, MDMA is closer to Mephedrone than NEP, which lacks the serotonin release effect and is significantly more stimulating at the same time. As a side note, with MDMA being found as the cut, it looks like 3-MMC and 4-MMC have finally graduated from "new psychoactive substances" class to a more permanent position.
Pills remain as unreliable as always. A brief change from PMMA we report weekly as of late (the danger is not over, it just had not been detected this week), this time we focus on the dosages found in pills. Some are completely bunk, like a pink Trump from Madrid (Spain) found to contain only caffeine. Then other can contain several strong doses of MDMA (120mg+), like the blue Farru pill from Barcelona detected with over 250 mg of MDMA. With median pill around 160 mg (already around x1.5 of a common dose), both significantly underdosed and overly potent tablets pose an increased risk of accidental overdose.
Scam of the Week
Samples that were not what they were sold as. Substitutions like these can be picked up with a test kit before anything is taken.
| Sold as | Actually | Samples |
|---|---|---|
| 4-MMC | Ketamine | 1 sample |
| Cocaine | Metamizole | 1 sample |
| Ketamine | Pregabalin | 1 sample |
Additional dishonourable mention: 2C-B pill sold in Bern (Switzerland) with only 1 mg of 2C-B.
Last Week at a Glance
- 43 samples from 4 countries (Austria, Germany, Spain and Switzerland) were included this week.
- 35 samples contained a quantified result, including 23 pills and 0 LSD samples.
- 12 samples contained more than one detected ingredient.
- No supported purity or content change was available for comparison.
What People Searched For
Below is a list of substances people are searching for in the DrugsPRO app when coming from Google, ordered by how often they were searched over the past week. Something suddenly on the rise can stand out in search interest before it shows up in lab results.
| # | Substance | Trend |
|---|---|---|
| 1 | Bromonordiazepam | cooling |
| 2 | NEP | cooling |
| 3 | Flubrotizolam | cooling |
| 4 | MGM-15 | cooling |
| 5 | 1Fe-LSD | cooling |
| 6 | MXPCP | cooling |
| 7 | Ethylflualprazolam | cooling |
| 8 | IC-26 | steady |
| 9 | 4-CMC | cooling |
| 10 | DMNPC | cooling |
Substances in Focus
Three substances covered in more detail this week: what they are, and how they are dosed and how long they last by route of administration. Doses and durations come from the DrugsPRO library and describe the substance itself, not any tested sample.
NEP
N-ethylpentedrone offers stimulating and mildly entactogenic effects but little is known about its chronic risks. Reports point to harsh comedowns and strong compulsions to redose, so apply the same caution used with other potent cathinones. Read more on dose.wiki
Source: tripsit.me, psychonautwiki.org
Oral
Dose range
Duration
Onset 0.17-0.33 hPeak 1-2 hOffset 2-4 h
Total: 3-6 h. After effects: 0.5-3 h.
Insufflated
Dose range
Duration
Onset 0.083-0.25 hCome-up 0.1-0.2 hPeak 0.5-1.5 hOffset 0.5-1.5 h
Total: 2-4 h. After effects: 0.5-2 h.
Smoked
Dose range
Duration
Onset 0.08 h
Source: dose.wiki, tripsit.me, psychonautwiki.org, substance.wiki
4-CMC
4-CMC is a synthetic cathinone structurally similar to mephedrone (4-MMC) and para-chloromethamphetamine. Research indicates it is neurotoxic through oxidative stress mechanisms and is more cytotoxic than 4-MMC. Common adverse effects include increased blood pressure, tachycardia, hyperthermia, anxiety, and paranoia. Read more on dose.wiki
Source: tripsit.me
Oral
Dose range
Duration
Onset 0.33-1 hPeak 1-3 hOffset 3-5 h
Total: 4-7 h. After effects: 6-24 h.
Insufflated
Dose range
Duration
Onset 0.02-0.08 hPeak 0.5-1.5 hOffset 1-2 h
Total: 1-3 h. After effects: 2-24 h.
Source: dose.wiki, tripsit.me, substance.wiki
Pregabalin
Pregabalin has greater than 90% oral bioavailability and is eliminated renally as unchanged drug with a mean half-life of 6.3 hours in normal renal function. Dose reductions required in chronic kidney disease. Read more on dose.wiki
Source: erowid.org, tripsit.me, psychonautwiki.org
Oral
Dose range
Duration
Onset 0.5-1.5 hCome-up 1-2 hPeak 1.5-3 hOffset 4-8 h
Total: 4-8 h. After effects: 4-10 h.
Rectal
Dose range
Duration
Onset 0.25-0.5 hCome-up 0.5-2 hPeak 2-3 hOffset 3-5 h
After effects: 6-12 h.
Insufflated
Dose range
Source: dose.wiki, tripsit.me, psychonautwiki.org, substance.wiki
Bars are drawn to the same scale within a substance. An open-ended band such as “175+ mg” is shown reaching the end of the scale.
Purity and Content
Below, the big number in each row is the typical result for 14–20 September 2026: half the samples came in stronger, half weaker. The smaller one in brackets is the same thing measured over the last twelve months.
No substance had enough quantified samples for this reporting period.
Most Common Adulterants and Other Impurities
Across the last 365 days, 1,955 mixed samples contained 135 distinct additional ingredients.
| Samples | Additional ingredient | Share of substance mixtures | Most often found with |
|---|---|---|---|
| 692 | Caffeine | 84.2% of amphetamine samples · higher than last week | Amphetamine, Heroin, MDMA |
| 271 | Unknown | 23.5% of MDMA samples · higher than last week | MDMA, Mephedrone, 2C substances |
| 161 | Paracetamol | 81.9% of heroin samples · higher than last week | Heroin, Cocaine, Ketamine |
| 110 | iso-LSD | 94.8% of LSD samples · lower than last week | LSD |
| 109 | MDMA | 44.2% of ketamine samples | Ketamine, 2C substances, Mephedrone |
| 108 | Procaine | 34.2% of cocaine samples · higher than last week | Cocaine, Ketamine, Mephedrone |
| 104 | 4-CMC | 34.8% of mephedrone samples · lower than last week | Mephedrone, MDMA, Ketamine |
| 100 | Ketamine | 18.7% of MDMA samples · lower than last week | MDMA, 2C substances, Amphetamine |
| 63 | Phenacetin | 16.2% of cocaine samples | Cocaine, Heroin, Ketamine |
| 58 | 2-MMC | 12.1% of mephedrone samples · lower than last week | Mephedrone, Ketamine, MDMA |
| 58 | Levamisole | 20.1% of cocaine samples · higher than last week | Cocaine, Ketamine |
| 42 | 4-BEC | 21.2% of mephedrone samples · higher than last week | Mephedrone, Ketamine |
| 42 | Cocaine | 12.3% of ketamine samples | Ketamine, Heroin, Amphetamine |
| 41 | Amphetamine | 5.2% of MDMA samples · lower than last week | MDMA, Ketamine, Cocaine |
| 35 | 2C-B | 8.6% of MDMA samples · lower than last week | MDMA, Ketamine, Amphetamine |
| 34 | 4-MMC | 6.7% of MDMA samples · higher than last week | MDMA, Ketamine, Cocaine |
| 31 | 1-PEA | 6.7% of amphetamine samples · higher than last week | Amphetamine, MDMA |
| 31 | DPIA | 6.9% of amphetamine samples · lower than last week | Amphetamine |
| 25 | d-8-Tetrahydrocannabinol | 29.4% of THC samples · lower than last week | THC/cannabinoids |
| 24 | NEP | 7.1% of mephedrone samples · lower than last week | Mephedrone, MDMA, Ketamine |
Impurities Detected This Week
MDMA: 2C-B (2), 2C-H (1), 4-MMC (1), NEP (1), Unknown (4)
Amphetamine: Caffeine (1), Unknown (1)
2C substances: MDMA (2), Unknown (4)
THC/cannabinoids: d-8-Tetrahydrocannabinol (1), Free Cbd (1), Free Thc (1)
Mephedrone: MDMA (1), Procaine (1), Unknown (1)
Remaining detected substances: 4-CMC (3), 4-HO-MET (1), Caffeine (1), MDPHP (1), Metamizole (1), NEP (3), Pregabalin (1), Tapentadol (2), Unknown (1)
Data Sources
This report is based on drug-checking data published by: addiction-neuchatel.ch, ailaket.com, checkit.wien, contact-suchthilfe.ch, drogart.org, drogenarbeitz6.at, drugchecking.berlin, drugchecking.ch, druglab.fr, DrugsData, École des sciences criminelles (ESC), energycontrol.org, IRM Basel, knowyourstuff.nz, neutravel.net, nightlifevaud.ch, nuit-blanche.ch, Pharmazeutischen Kontrolllabor Bern, raveitsafe.ch, Reseachem GmbH, saferdancebasel.ch, SaferParty.ch, stoftest.org, tragwerk-luzern.ch, Trimbos, triptalks.at, Université Lausanne, wedinos.wales.
All of this data is available at your fingertips in the DrugsPRO app for Android, iOS, and the web.
Drug-checking results describe tested samples only and are not representative of the entire market.
DrugsPRO App
Journaling & Drug Checking
Private journaling, guided test interpretation, lab alerts and reference tools in one offline-first app. Your data stays on your device.
No test result can tell you a substance is safe. No substance is 100% safe.This article is published for harm reduction purposes. It does not encourage the use of psychoactive substances and does not replace medical advice.