Mecke Reagent Test Instructions
The Mecke reagent test is a chemical reagent used in the field of drug analysis. It is primarily employed to identify specific substances, particularly alkaloids and other compounds. This test is known for its capability to detect various substances, including opioids and other drugs. Invented by Austrian chemist Alois Mecke, the reagent gained prominence for its ability to distinguish between different substances based on the color changes that occur upon reaction. As a result, it has become a crucial tool in the arsenal of forensic and harm reduction services, aiding in the identification and analysis of illicit substances.
Mecke reagent colour reactions
Expected colour changes for the Mecke reagent, from the PRO Test reagent chart.
| Substance | Expected reaction |
|---|---|
| 2C-B | Yellow → olive |
| DMT | Brown / green |
| LSD | No instant reaction |
| Ketamine | No colour change |
| Amphetamine | No colour change |
| Methamphetamine | Yellow |
| Mephedrone | No colour change |
| MDA | Instant green → black |
| MDMA | Instant green → black |
| Cocaine | No colour change |
| Oxycodone | Faint yellow |
Reagents indicate presence, not purity or quantity. A reaction that differs from the expected colour is a reason to test further, not proof of a particular substance.

Mecke reagent is a common drug testing kit for crystals, powders or pills. Mecke test is best for 2C-B, cocaine, DMT, MDMA, meth/amphetamine, opioids and more.
How to test?
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A positive or negative Mecke testing kit result does not indicate if a substance is safe. No substance is 100% safe.
This article does not encourage the use of psychoactive substances and does not replace medical advice.


