Simon's Reagent Test Instructions
Simon’s reagent test is a chemical colorimetric test used for the detection of secondary amines. By adding the reagent to a sample, a characteristic blue color change occurs, indicating the presence of these compounds. Simon’s reagent test has found extensive application in forensic and drug testing contexts, aiding in the identification of various substances including certain drugs and alkaloids. Its simple yet effective methodology has made it a popular tool for rapid and preliminary screening in diverse fields, contributing significantly to the advancement of chemical analysis techniques.
Simon’s reagent colour reactions
Expected colour changes for the Simon’s reagent, from the PRO Test reagent chart.
| Substance | Expected reaction |
|---|---|
| 2C-B | No blue colour change |
| DMT | Black precipitate |
| LSD | No blue colour change |
| Ketamine | No blue colour change |
| Amphetamine | No blue colour change |
| Methamphetamine | Instant dark blue |
| Mephedrone | Slow blue |
| MDA | No blue colour change |
| MDMA | Instant dark blue |
| Cocaine | No blue colour change |
| Oxycodone | Dark pink |
Reagents indicate presence, not purity or quantity. A reaction that differs from the expected colour is a reason to test further, not proof of a particular substance.
Simon’s reagent is the main drug testing kit for secondary amines. Simon’s test is best for MDMA, methamphetamine, mephedrone, PMMA and more.
How to test?
Questions?
Still searching for the best test kit?
Click here to see our full offer, or here for single-use kits, or here for all multi-use kits including TLC purity testing kits.
A positive or negative Simon’s reagent test kit result does not indicate if a substance is safe. No substance is 100% safe.
This article does not encourage the use of psychoactive substances and does not replace medical advice.


